From Portland, take I-84 East. Exit at Corbett (Exit 22) onto the Historic Columbia River Highway. The waterfalls unfold in sequence along this winding, scenic road. Total driving between stops is minimal. Budget 2-3 hours for all four at a relaxed pace.
If the top picks are full, Higgins Restaurant & Bar (SW downtown) does contemporary French-American with locally sourced ingredients and a lively bar scene. Or head to Horse Brass Pub (SE Belmont) for a legendary English pub with a deep tap list, darts, and classic pub fare. Neither requires reservations and both are excellent fallbacks.
The route flows naturally without backtracking: Camas west to Portland (brunch), east through the Gorge (waterfalls), loop back to Portland (beer + dinner), then east on I-84 back to Camas. Simple, scenic, zero stress.